SFR's form-based score for this saved formula; it is not an absorption percentage.
Life Extension, Two-Per-Day Multivitamin, 120 Tablets
Life Extension Two-Per-Day Multivitamin, 120 Tablets is a high-potency two-tablet formula with a Bioavailability Index of 4.25. It uses L-5-MTHF folate, methylcobalamin B12 and vitamin D3; magnesium is 100 mg as magnesium oxide.

Key Facts
Fast product-level facts before the full review.
Take in divided doses with meals; the bottle contains 60 labeled servings.
Provides 250% DV per 2-tablet serving as cholecalciferol.
Iron is not listed as a nutrient in the supplied 120-tablet Supplement Facts.
Folate uses L-5-MTHF, B12 methylcobalamin, vitamin D cholecalciferol, and zinc includes L-OptiZinc®.
Boron and molybdenum are amino-acid chelates; zinc is mixed, while magnesium is magnesium oxide.
Magnesium provides 24% DV per serving; SFR rates magnesium oxide Low for form-based bioavailability.
Life Extension Two-Per-Day Supplement Facts & Bioavailability Review
Supplement Facts & Bioavailability
Full ingredient list with serving amounts, Daily Values, and bioavailability levels.
| Ingredient | Amount Per Serving | % Daily Value | Bioavailability Level | ||
|---|---|---|---|---|---|
| Vitamin A (as beta-carotene, acetate) (5,000 IU) | 1500 mcg^ | 167% | Up. Medium | ||
Up. Medium | |||||
| Vitamin C (as ascorbic acid, calcium and niacinamide ascorbates) | 470 mg | 522% | High | ||
High | |||||
| Vitamin D3 (as cholecalciferol) (2,000 IU) | 50 mcg | 250% | High | ||
High | |||||
| Vitamin E (as D-alpha tocopheryl succinate, D-alpha tocopherol) | 67 mg | 447% | High | ||
High | |||||
| Thiamine (vitamin B1) (as thiamine HCl) | 75 mg | 6250% | High | ||
High | |||||
| Riboflavin (vitamin B2) (as riboflavin, riboflavin 5'-phosphate) | 50 mg | 3846% | Up. Medium | ||
Up. Medium | |||||
| Niacin (as niacinamide, niacinamide ascorbate) | 50 mg° | 313% | High | ||
High | |||||
| Vitamin B6 (as pyridoxine HCl, pyridoxal 5'-phosphate) | 75 mg | 4412% | Up. Medium | ||
Up. Medium | |||||
| Folate (as L-5-methyltetrahydrofolate calcium salt) | 680 mcg° | 170% | High | ||
High | |||||
| Vitamin B12 (as methylcobalamin) | 300 mcg | 12500% | High | ||
High | |||||
| Biotin | 300 mcg | 1000% | High | ||
High | |||||
| Pantothenic acid (as D-calcium pantothenate) | 50 mg | 1000% | High | ||
High | |||||
| Iodine (as potassium iodide) | 150 mcg | 100% | High | ||
High | |||||
| Magnesium (as magnesium oxide) | 100 mg | 24% | Low | ||
Low | |||||
| Zinc (as zinc citrate, L-OptiZinc® zinc mono-L-methionine sulfate) | 25 mg | 227% | High | ||
High | |||||
| Selenium [as sodium selenite, SelenoExcell® high selenium yeast, Se-methyl L-selenocysteine] | 200 mcg | 364% | High | ||
High | |||||
| Manganese (as manganese citrate, gluconate) | 2 mg | 87% | Up. Medium | ||
Up. Medium | |||||
| Chromium [as Crominex® 3+ chromium stabilized with Capros® amla extract (fruit), PrimaVie® Shilajit] | 200 mcg | 571% | Superior | ||
Superior | |||||
| Molybdenum (as molybdenum amino acid chelate) | 100 mcg | 222% | High | ||
High | |||||
| Inositol | 50 mg | ** | High | ||
High | |||||
| Alpha lipoic acid | 25 mg | ** | High | ||
High | |||||
| Natural mixed tocopherols (providing gamma, delta, alpha, beta) | 20 mg | ** | High | ||
High | |||||
| Bio-Quercetin® Proprietary Blend providing 35% quercetin (5 mg) [from Japanese sophora concentrate (flower bud)], 30% galactomannans (4 mg) [from fenugreek (seed)] | 14 mg | ** | Superior | ||
Superior | |||||
| Marigold extract (Tagetes erecta)(flower)[std. to 5 mg trans-lutein, 155 mcg trans-zeaxanthin] | 11.12 mg | ** | High | ||
High | |||||
| Apigenin | 5 mg | ** | Low | ||
Low | |||||
| Boron (as boron amino acid chelate) | 3 mg | ** | High | ||
High | |||||
| Lycopene [from LycoBeads® natural tomato extract (fruit)] | 1 mg | ** | High | ||
High | |||||
| **Daily Value not established.^RAE (retinol activity equivalent). °DFE (dietary folate equivalent). •NE (niacin equivalent). | |||||
| Microcrystalline cellulose, stearic acid, croscarmellose sodium, dicalcium phosphate, food starch modified, silica, vegetable stearate, maltodextrin, coating (purified water, hypromellose, glycerin), sunflower lecithin, sunflower oil. | |||||
Summary
Life Extension Two-Per-Day Multivitamin, 120 Tablets is a high-potency two-tablet multivitamin with a vitamin-heavy dose profile and clearly disclosed nutrient forms.
The clearest strength is form transparency: the label identifies methylfolate, methylcobalamin, vitamin D3, mixed vitamin E forms, and a mixed zinc system that includes L-OptiZinc®. The clearest tradeoff is the mineral block: magnesium contributes 100 mg (24% DV) and is supplied as magnesium oxide.
This formula is best understood as a high-potency option rather than a near-Daily-Value multivitamin.
High-Potency Dosing Is the Defining Choice
The defining dose choice is an aggressive B-vitamin profile. Vitamin B1 provides 75 mg (6250% DV), vitamin B6 75 mg (4412% DV), and vitamin B12 300 mcg (12500% DV); vitamins C, D3, and E are also supplied above 200% DV.
That pattern matters more than the raw ingredient count: users looking for conservative daily coverage should recognize that this formula is positioned and dosed as high potency. The mineral contribution is less even, with magnesium at 100 mg (24% DV).
Which Two-Per-Day Variant Does This Review Cover?
Life Extension Two-Per-Day is available in tablet and capsule formats, with 60-count and 120-count bottle options. We compared the Supplement Facts across the 60-tablet, 120-tablet, 60-capsule, and 120-capsule versions. The active nutrient formula appears identical; the main difference is bottle size and delivery format.
| Variant | What changes | How to use this review |
|---|---|---|
| 120 Tablets | Tablet format, larger bottle | This is the exact variant analyzed on this page. |
| 60 Tablets | Same tablet formula, smaller bottle | The Supplement Facts appear identical to the 120-tablet version; only the count changes. |
| 120 Capsules | Same active formula, capsule format | The Supplement Facts appear identical to the tablet version; the difference is mainly delivery format and inactive ingredients. |
| 60 Capsules | Same capsule formula, smaller bottle | The Supplement Facts appear identical to the 120-capsule version; only the count changes. |
The Bioavailability Index on this page should be understood as an analysis of the Two-Per-Day active nutrient formula, not only of one bottle size. For the checked variants, the Supplement Facts appear identical, so the BI interpretation is the same. The practical choice is mainly about tablet vs capsule format, bottle size, price per serving, and availability.
The delivery-format differences between tablets and capsules are covered in the next section.
Tablets vs Capsules: Same Supplement Facts, Different Delivery Format
Life Extension Two-Per-Day is available in both tablet and capsule formats. Based on the compared Supplement Facts, the active vitamin and mineral formula appears identical, so the Bioavailability Index applies to the formula rather than only to the 120-tablet bottle.
The practical difference is mainly in the delivery format and inactive ingredients. Tablets are a compressed solid form, while capsules contain the formula inside a vegetable cellulose capsule shell. This does not automatically mean that one version is more bioavailable than the other; the active nutrient forms remain the key factor.
| Format | What is different | Who may prefer it |
|---|---|---|
| Tablets | Includes stearic acid, croscarmellose sodium, and a coating made with purified water, hypromellose, and glycerin. | Users who are comfortable with coated compressed tablets and do not mind standard tablet excipients. |
| Capsules | Uses a vegetable cellulose capsule shell instead of a tablet coating and disintegrant system. | Users who prefer capsule format or want to avoid the additional tablet coating and croscarmellose sodium. |
Both versions share several inactive ingredients, including dicalcium phosphate, modified food starch, silica, vegetable stearate, microcrystalline cellulose, maltodextrin, sunflower lecithin, and sunflower oil.
Bottom line: if the current labels remain identical, the choice between tablets and capsules is mostly about swallowing preference, tolerance of inactive ingredients, price, and availability — not about a different nutrient profile.
For a side-by-side SKU-level view, see the Life Extension Two-Per-Day 120 Capsules vs 120 Tablets comparison.
Form Choices: Strong Disclosure, Uneven Minerals
The label makes several important form choices easy to audit. Folate is supplied as calcium L-5-methyltetrahydrofolate, vitamin B12 as methylcobalamin, and zinc combines zinc citrate with L-OptiZinc® zinc mono-L-methionine sulfate.
Bio-Quercetin® is disclosed as a 14 mg proprietary blend providing 5 mg quercetin and 4 mg galactomannans, so the branded name can be read together with the actual blend specification.
The mineral strategy is selective rather than uniformly chelated: boron and molybdenum are amino-acid chelates, while magnesium remains magnesium oxide. The formula therefore has detailed form disclosure without using the same delivery strategy across every mineral.
Label Claims and Suggested Use
The product is labeled Gluten Free, Soy-free, and Non-GMO LE Certified. The supplied evidence does not document a vegetarian or vegan claim, and it does not include a product-specific testing claim.
Suggested use is two tablets daily in divided doses with meals. The label also says not to exceed the recommended dose, to keep the product out of reach of children, and to consult a physician if undergoing treatment for a medical condition or if pregnant or lactating.
For vitamin D, the label specifically advises periodic serum 25-hydroxy vitamin D measurement for individuals consuming more than 50 mcg (2,000 IU) per day from diet and supplements.
Who This Formula Fits Best
This formula is a better fit for users who want a broad, high-potency multivitamin in two daily tablets and who pay attention to named nutrient forms rather than only ingredient count.
It is less aligned with preferences for near-Daily-Value dosing, a one-unit routine, or substantial magnesium coverage. The supplied Supplement Facts also do not list iron as a nutrient, which matters for buyers specifically looking for an iron-containing multivitamin.
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Frequently Asked Questions
Is this review for the 120-tablet or capsule version?
What is the serving size for Life Extension Two-Per-Day 120 Tablets?
How potent is Life Extension Two-Per-Day compared with Daily Values?
Which ingredient forms stand out in Life Extension Two-Per-Day?
Does Life Extension Two-Per-Day contain iron?
Is Life Extension Two-Per-Day vegetarian or vegan?
Disclaimer
The information provided on this website is for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a healthcare professional for any health-related questions or concerns.